Novel cerebrospinal fluid inflammatory biomarkers in neonatal post-hemorrhagic hydrocephalus
نویسندگان
چکیده
منابع مشابه
Cerebrospinal fluid biomarkers of infantile congenital hydrocephalus
INTRODUCTION Hydrocephalus is a complex neurological disorder with a pervasive impact on the central nervous system. Previous work has demonstrated derangements in the biochemical profile of cerebrospinal fluid (CSF) in hydrocephalus, particularly in infants and children, in whom neurodevelopment is progressing in parallel with concomitant neurological injury. The objective of this study was to...
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Background : Meningitis is more common during the neonatal period than other periods of life and has a prevalence of one in 1000 live births. The similarity of its clinical manifestations with other infectious diseases makes it difficult to diagnose. The aim of the current study was to determine the relationship between age, sex, clinical signs and symptoms and laboratory test results of ne...
متن کاملBiomarkers in Neonatal Posthemorrhagic Hydrocephalus
Posthemorrhagic hydrocephalus (PHH) is a rare but serious outcome among premature babies in the NICU, with consequences including mortality and severe neurodevelopmental disabilities. The causes of PHH are still not entirely understood, and its prevention and treatment are controversial. Various cerebrospinal fluid biomarkers have been studied in infants with PHH in order to recognize the cause...
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BACKGROUND Neurological outcomes of preterm infants with post-hemorrhagic hydrocephalus (PHH) remain among the worst in infancy, yet there remain few instruments to inform the treatment of PHH. We previously observed PHH-associated elevations in cerebrospinal fluid (CSF) amyloid precursor protein (APP), neural cell adhesion molecule-L1 (L1CAM), neural cell adhesion molecule-1 (NCAM-1), and othe...
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ژورنال
عنوان ژورنال: Fluids and Barriers of the CNS
سال: 2015
ISSN: 2045-8118
DOI: 10.1186/2045-8118-12-s1-o19